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CFSRE and Verogen Team Up to Accelerate the Implementation of Next Generation Sequencing for Law Enforcement and Practitioner Communities
  • Sep 9, 2019
  • Latest News

The Center for Forensic Science Research & Education (CFSRE) and Verogen have entered into a collaborative agreement to establish CFSRE as a leader in the field of forensic Next Generation Sequencing (NGS), also known as Massively Parallel DNA Sequencing (MPS).

CFSRE, supported through this collaboration, has recently completed their validation of the ForenSeq DNA Signature Prep Kit on the MiSeq FGx® platform.  In the coming months, CFSRE will be working to develop training materials for law enforcement and practitioner communities, and implementing a high-quality workflow for application with casework services.

“We are very excited to be working with Verogen on the forefront of evaluating and implementing this new technology,” said Dr. Barry Logan, Executive Director at CFSRE.  “The evaluation of new technologies that can be applied to criminal investigations is an important component of our organization’s mission.”

With this technology, a single DNA test provides a wealth of information to aid investigations along multiple vectors.  The included autosomal short tandem repeat (STR) markers can be used to populate and search the CODIS U.S. National DNA Index (NDIS).  The same test also provides Y-STR results for profiling male subjects, X-STR results for complicated kinship scenarios, and a large number of single nucleotide polymorphism (SNP) markers to assist with low quality samples typical in forensic contexts.  Additionally, a collection of these SNPs can provide information about appearance, such as hair color, eye color, and biogeographical ancestry, to aid stalled cases with investigative leads or to rapidly refine a subject pool.  This new toolbox uses best-in-class sequencing technology to add significant depth and breadth to forensic DNA analysis, while enabling recovery of results from biological evidence samples for which traditional methods have proven inadequate.